Course Content
Matter
OBJECTIVES By the end of this topic, the trainee should be able to 1.Define matter 2.Explain state of matter 3.Distinguish between physical and chemical changes 4.Explain the gas laws
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Atoms , Elements and Compounds
OBJECTIVES By the end of this topic , the trainee should be able to; 1.Define Elements, Compounds and Mixtures 2.Describe the structure of an atom 3.Describe how to determine the Atomic number ,Mass number and Isotopes
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The Periodic Table
OBECTIVES By the end of this topic, the trainee should be able to : 1.State the historical contribution on development of the periodic table 2.Explain the periodic trends of elements and their compounds 3.State the diagonal relationships of the periodic table
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The S-Block Element
OBJECTIVES By the end of this topic, the trainee should be able to: 1.Explain the chemistry of group I and II elements 2.State the application of group I and two elements and their compounds
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Chemical Bonds
OBJECTIVES By the end of these topic, the trainee should be able to 1.Identify different types of bonds 2.Describe their properties
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Chemical Equilibrium
OBJECTIVES By the end of this topic , the trainee should be able to : 1.Define chemical equilibria 2.Explain types of equilibria 3.Determine equilibrium constant 4.Describe factors affecting chemical equilibrium
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Introduction To Organic Chemistry
By the end of this topic , the trainee should be able to : 1.Explain the aspects of organic chemistry 2.Describe hydrocarbons 3.Classify organic molecules explain chemical reactions of simple organic molecules 4.Explain the properties , synthesis and uses of simple organic molecules
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Acids, Bases and Salts
OBJECTIVES By the end of this session , the trainee should be able to : 1.State properties of acids and bases 2.Differentiate between strong and weak acids 3.Explain types and properties of salts
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PH Analysis
OBJECTIVES By the end of this topic, the trainee should be able to: 1.Define the term PH 2.Explain the basic theory of PH 3.State the relationship between PH and color change in indicators 4.Explain the term buffer solution 5.Describe the preparation of buffer solutions 6.State the application of buffer solutions
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Sampling and Sample Preparation
OBJECTIVE By the end of this topic, the trainee should be able to : 1.Define the terms used in sample preparation 2.State the importance of sampling 3.Describe the techniques of sampling 4.Describe the procedure for sample pre-treatment 5.State sample storage methods
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Separation Techniques
OBJECTIVES By the end of this topic , the trainee should be able to : 1.Define separation, extraction and purification 2.Describe the separation , extraction and purification techniques 3.Explain the methods of determining purity of substances
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Heating and Cooling Techniques
OBJECTIVES To identify various techniques used for heating and cooling substances in the laboratory
Heating and Cooling Techniques
OBJECTIVES To identify various techniques used for heating and cooling substances in the laboratory
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Distillation Techniques
By end of this topic, Trainee should be able to : 1. Define distilation 2. State and explain various distillation techniques 3. Outline Various distillation techniques 4. Outline the applications of Distillation techniques
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Crystallization Techniques
OBJECTIVES By the end of the topic, the learner should be able to: 1.To define crystallization 2.To describe crystallization process 3.To carry out crystallization procedure
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Solvent Extraction Techniques
OBJECTIVES By the end of the topic, the learner should be able to 1.Define solvent extraction 2.Explain terms used in solvent extraction 3.Describe methods of solvent extraction 4.Describe selection of appropriate solvents for solvent extraction 5.Determine distribution ration 6.Outline factors actors influencing the extraction efficiency 7.Describe Soxhlet extraction
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Chromatography Techniques
OBJECTIVES By the end of this topic, the learner should be able to: 1.Define chromatography techniques 2.Explain terms used in chromatography techniques 3.Describe principles of chromatography techniques 4.Explain types of chromatography techniques 5.Carry out chromatography experiments 6.Determine RF factor 7.Outline electrophoresis
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Titrimetric Analysis
OBJECTIVES By the end of this topic, the trainee should be able to: 1.Define terms used in titrimetric analysis 2.Describe types of titrimetric analysis 3.Balance chemical reactions 4.Work out calculations involved in titrimetric analysis
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Redox Titration
Redox Titration is a laboratory method of determining the concentration of a given analyte by causing a redox reaction between the titrant and the analyte. Redox titration is based on an oxidation-reduction reaction between the titrant and the analyte. It is one of the most common laboratory methods used to identify the concentration of unknown analytes. Redox reactions involve both oxidation and reduction. The key features of reduction and oxidation are discussed below.
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Complexiometric Titration
omplexometric Titration or chelatometry is a type of volumetric analysis wherein the colored complex is used to determine the endpoint of the titration. The method is particularly useful for determination of the exact number of a mixture of different metal ions, especially calcium and magnesium ions present in water in solution .
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Gravimetric Analysis
OBJECTIVES By the end of this topic, the trainee should be able to: 1.Define gravimetric analysis 2.Describe the principles of gravimetric analysis 3.Describe the steps involved in gravimetric analysis 4.Explain factors affecting gravimetric analysis 5.Describe the equipments and apparatus used in gravimetric analysis 6.Carry out gravimetric analysis
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Calorimetric Analysis
OBJECTIVES By the end of this topic, the trainee should be able to: 1.Define terms and units used in thermochemistry 2.Determine enthalpy changes in chemical reactions 3.Determine heat capacity and specific heat capacity 4.Compare calorific values of different materials 5.Determine different heat reactions 6.Apply law of conservation of energy and Hess law in thermochemical calculations
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Chemistry Techniques for Science Laboratory Technicians
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ALKANOLS (ALCOHOLS)

Alcohols are those organic compounds which are characterized by the presence of one, two or more hydroxyl groups (−OH) that are attached to the carbon atom in an alkyl group or hydrocarbon chain.

The simplest alkanol is methanol (CH3OH). Its common name wood alcohol comes from the fact that it was first obtained by heating wood in the absence of air. Methanol is very poisonous; consumption of less than two teaspoons can cause blindness. Of all the alkanols, methanol is produced in the greatest quantities in industry.

Ethanol (CH3CH2OH) or simply, alcohol in layman‟s terms has been prepared since antiquity by fermentation of sugars and starches, catalyzed by yeast. Sugars for fermentation come from a variety of sources, including grains, grape juice, various vegetables and agricultural wastes. The immediate product of fermentation is a water solution containing up to 15% ethanol (its not surprising that home brew can be so potent!). This value can be increased by distillation.

Classification of alcohols

Alcohols are differentiated based upon the presence of hydroxyl group attached. The location of this hydroxyl group as well will change the physical and chemical properties of any alcohol.

There are three types of alcohol. Alcohols are classified as primary, secondary or tertiary alcohols.

 Types of Alcohols

The classification is done in accordance to where the carbon atom of an alkyl group is attached to the hydroxyl group.

  1. Primary Alcohols

Primary alcohols are those alcohols where the carbon atom of the hydroxyl group (OH) is attached to only one single alkyl group. Some examples of these primary alcohols include Methanol (propanol), ethanol, etc. The complexity of this alkyl chain is unrelated to the classification of any alcohol considered as primary. The existence of only one linkage among –OH group and an alkyl group and the thing that qualifies any alcohol as a primary.

  1. Secondary Alcohols

Secondary alcohols are those where the carbon atom of the hydroxyl group is attached to two alkyl groups on either side. The two alkyl groups present may be either structurally identical or even different. Some examples of secondary alcohols are given below.

  1. Tertiary Alcohols

Tertiary alcohols are those which feature hydroxyl group attached to the carbon atom which is connected to 3- alkyl groups. The physical properties of these alcohols mainly depend on their structure. The presence of this -OH group allows the alcohols in the formation of hydrogen bonds with their neighbouring atoms. The bonds formed are weak, and this bond makes the boiling points of alcohols higher than its alkanes. The examples of tertiary alcohols include-

 Most of the alcohols are known to be colourless liquids or even are said to behave as solid at room temperatures.

 Alcohols with less molecular weight are said to be highly soluble in water; and with their increase in molecular weight, they tend to become less soluble and their vapour pressures, boiling points, densities, and the viscosities to increase.

Nomenclature of alkanols

The systematic name for an alkanol is obtained by following the rules listed below:

  1. Find the longest chain that contains the -OH group.The stem of the alkanols name is obtained from the parent alkane, with the -e being replacedby the suffix -ol.
  2. The position of the -OH group is specified by a numberchosen so that it is the smallest of the substituent numbers.

Properties of Alcohols

Alcohols are organic compounds in which a hydrogen atom of an aliphatic carbon is replaced with a hydroxyl group. Thus an alcohol molecule consists of two parts; one containing the alkyl group and the other containing functional group hydroxyl group. They have a sweet odour. They exhibit a unique set of physical and chemical properties.

The physical and chemical properties of alcohols are mainly due to the presence of hydroxyl group.

Physical Properties of Alcohol

  1. The Boiling Point of Alcohols

Alcohols generally have higher boiling points in comparison to other hydrocarbons having equal molecular masses. This is due to the presence of intermolecular hydrogen bonding between hydroxyl groups of alcohol molecules. In general, the boiling point of alcohols increases with an increase in the number of carbon atoms in the aliphatic carbon chain. On the other hand, the boiling point decreases with an increase in branching in aliphatic carbon chains the Van der Waals forces decreases with a decrease in surface area. Thus, primary alcohols have a higher boiling point.

  1. Solubility of Alcohols

The solubility of alcohol in water is governed by the hydroxyl group present. The hydroxyl group in alcohol is involved in the formation of intermolecular hydrogen bonding. Thus, hydrogen bonds are formed between water and alcohol molecules which make alcohol soluble in water. However, the alkyl group attached to the hydroxyl group is hydrophobic in nature. Thus, the solubility of alcohol decreases with the increase in the size of the alkyl group.

  1. The Acidity of Alcohols

Alcohols react with active metals such as sodium, potassium etc. to form the corresponding alkoxide. These reactions of alcohols indicate their acidic nature. The acidic nature of alcohol is due to the polarity of –OH bond. The acidity of alcohols decreases when an electron-donating group is attached to the hydroxyl group as it increases the electron density on the oxygen atom. Thus, primary alcohols are generally more acidic than secondary and tertiary alcohols. Due to the presence of unshared electrons on the oxygen atom, alcohols act as Bronsted bases too.

Chemical Properties of Alcohols

Alcohols exhibit a wide range of spontaneous chemical reactions due to the cleavage of the C-O bond and O-H bond. Some prominent chemical reactions of alcohols are:

  1. Oxidation of Alcohol
  • Alcohols undergo oxidation in the presence of an oxidizing agent to produce aldehydes and ketones which upon further oxidation give carboxylic acids.

2. Dehydration of Alcohol

  • Upon treatment with protic acids, alcohols undergo dehydration (removal of a molecule of water) to form alkenes. Dehydration of alcohol


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