Course Content
Matter
OBJECTIVES By the end of this topic, the trainee should be able to 1.Define matter 2.Explain state of matter 3.Distinguish between physical and chemical changes 4.Explain the gas laws
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Atoms , Elements and Compounds
OBJECTIVES By the end of this topic , the trainee should be able to; 1.Define Elements, Compounds and Mixtures 2.Describe the structure of an atom 3.Describe how to determine the Atomic number ,Mass number and Isotopes
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The Periodic Table
OBECTIVES By the end of this topic, the trainee should be able to : 1.State the historical contribution on development of the periodic table 2.Explain the periodic trends of elements and their compounds 3.State the diagonal relationships of the periodic table
0/3
The S-Block Element
OBJECTIVES By the end of this topic, the trainee should be able to: 1.Explain the chemistry of group I and II elements 2.State the application of group I and two elements and their compounds
0/4
Chemical Bonds
OBJECTIVES By the end of these topic, the trainee should be able to 1.Identify different types of bonds 2.Describe their properties
0/2
Chemical Equilibrium
OBJECTIVES By the end of this topic , the trainee should be able to : 1.Define chemical equilibria 2.Explain types of equilibria 3.Determine equilibrium constant 4.Describe factors affecting chemical equilibrium
0/6
Introduction To Organic Chemistry
By the end of this topic , the trainee should be able to : 1.Explain the aspects of organic chemistry 2.Describe hydrocarbons 3.Classify organic molecules explain chemical reactions of simple organic molecules 4.Explain the properties , synthesis and uses of simple organic molecules
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Acids, Bases and Salts
OBJECTIVES By the end of this session , the trainee should be able to : 1.State properties of acids and bases 2.Differentiate between strong and weak acids 3.Explain types and properties of salts
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PH Analysis
OBJECTIVES By the end of this topic, the trainee should be able to: 1.Define the term PH 2.Explain the basic theory of PH 3.State the relationship between PH and color change in indicators 4.Explain the term buffer solution 5.Describe the preparation of buffer solutions 6.State the application of buffer solutions
0/5
Sampling and Sample Preparation
OBJECTIVE By the end of this topic, the trainee should be able to : 1.Define the terms used in sample preparation 2.State the importance of sampling 3.Describe the techniques of sampling 4.Describe the procedure for sample pre-treatment 5.State sample storage methods
0/5
Separation Techniques
OBJECTIVES By the end of this topic , the trainee should be able to : 1.Define separation, extraction and purification 2.Describe the separation , extraction and purification techniques 3.Explain the methods of determining purity of substances
0/2
Heating and Cooling Techniques
OBJECTIVES To identify various techniques used for heating and cooling substances in the laboratory
Heating and Cooling Techniques
OBJECTIVES To identify various techniques used for heating and cooling substances in the laboratory
0/1
Distillation Techniques
By end of this topic, Trainee should be able to : 1. Define distilation 2. State and explain various distillation techniques 3. Outline Various distillation techniques 4. Outline the applications of Distillation techniques
0/3
Crystallization Techniques
OBJECTIVES By the end of the topic, the learner should be able to: 1.To define crystallization 2.To describe crystallization process 3.To carry out crystallization procedure
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Solvent Extraction Techniques
OBJECTIVES By the end of the topic, the learner should be able to 1.Define solvent extraction 2.Explain terms used in solvent extraction 3.Describe methods of solvent extraction 4.Describe selection of appropriate solvents for solvent extraction 5.Determine distribution ration 6.Outline factors actors influencing the extraction efficiency 7.Describe Soxhlet extraction
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Chromatography Techniques
OBJECTIVES By the end of this topic, the learner should be able to: 1.Define chromatography techniques 2.Explain terms used in chromatography techniques 3.Describe principles of chromatography techniques 4.Explain types of chromatography techniques 5.Carry out chromatography experiments 6.Determine RF factor 7.Outline electrophoresis
0/6
Titrimetric Analysis
OBJECTIVES By the end of this topic, the trainee should be able to: 1.Define terms used in titrimetric analysis 2.Describe types of titrimetric analysis 3.Balance chemical reactions 4.Work out calculations involved in titrimetric analysis
0/6
Redox Titration
Redox Titration is a laboratory method of determining the concentration of a given analyte by causing a redox reaction between the titrant and the analyte. Redox titration is based on an oxidation-reduction reaction between the titrant and the analyte. It is one of the most common laboratory methods used to identify the concentration of unknown analytes. Redox reactions involve both oxidation and reduction. The key features of reduction and oxidation are discussed below.
0/5
Complexiometric Titration
omplexometric Titration or chelatometry is a type of volumetric analysis wherein the colored complex is used to determine the endpoint of the titration. The method is particularly useful for determination of the exact number of a mixture of different metal ions, especially calcium and magnesium ions present in water in solution .
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Gravimetric Analysis
OBJECTIVES By the end of this topic, the trainee should be able to: 1.Define gravimetric analysis 2.Describe the principles of gravimetric analysis 3.Describe the steps involved in gravimetric analysis 4.Explain factors affecting gravimetric analysis 5.Describe the equipments and apparatus used in gravimetric analysis 6.Carry out gravimetric analysis
0/8
Calorimetric Analysis
OBJECTIVES By the end of this topic, the trainee should be able to: 1.Define terms and units used in thermochemistry 2.Determine enthalpy changes in chemical reactions 3.Determine heat capacity and specific heat capacity 4.Compare calorific values of different materials 5.Determine different heat reactions 6.Apply law of conservation of energy and Hess law in thermochemical calculations
0/4
Chemistry Techniques for Science Laboratory Technicians
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ALKANALS AND ALKANONES

Aldehydes and ketones incorporate a carbonyl functional group

-C=O

These are organic compounds with structures -CHO and RC(=O)R’, where R and R’ represent carbon-containing substituents respectively.

In aldehydes, the carbonyl group has one hydrogen atom attached to it together with either a 2nd hydrogen atom or a hydrogen group which may be an alkyl group or one containing a benzene ring.

Example:

One can notice that all these have the exact same end to the molecule. The only difference is the complexity of the other attached group.

In ketones, the carbonyl group has 2 hydrocarbon groups attached to it. These can be either the ones containing benzene rings or alkyl groups. Ketone does not have a hydrogen atom attached to the carbonyl group.

 Example:

Propane is generally written as CH3COCH3.  In pentanone, the carbonyl group could be in the middle of the chain or next to the end – giving either pentan-3-one or pentan-2-one.

Properties of Aldehydes

  • The structure of aldehydes shows a sphybridized central carbon which is doubly connected to oxygen and has a single bond with hydrogen.
  • Small aldehydes are quite soluble in water.
  • Formaldehyde and acetaldehyde are great examples of this. These two aldehydes are quite important industrially.
  • Aldehydes generally exhibit a tendency to undergo oligomerization or polymerization.
  • The carbonyl centre of the aldehyde has an electron-withdrawing nature. Therefore, the aldehyde group can be considered somewhat polar.

Nomenclature of Aldehydes

  • Acyclic and Aliphatic Aldehydes are named after their longest carbon chain along with the “-al” suffix. For example, CH3CH3CH2CHO is called butanal since it has four carbons in the chain.
  • When the aldehyde functional group is added to a ring, the “-carbaldehyde” suffix must be used. For example, C6H11CHO is called cyclohexanecarbaldehyde.
  • In the case of natural compounds or carboxylic acids, “-oxo” is used as a prefix to highlight the carbon which is a part of the aldehyde functional group. For example, (CHO)-CH2COOH is called 3-oxopropanoic acid.

Some common and IUPAC names for some aldehydes are tabulated below.

Formula

Common name

IUPAC name

HCHO

Formaldehyde

Methanal

CH3CHO

Acetaldehyde

Ethanal

CH3-CH(CH3)-CHO

Isobutyraldehyde

2-Methylpropanal

CH3-CH=CH-CHO

Crotonaldehyde

2-Butenal

Properties of Ketones

  1. Ketones are polar in nature due to the presence of a polar carbonyl group. Therefore they have higher boiling points than non-polar compounds.
  2. It cannot form any intermolecular hydrogen bond-like alcohols because there is no hydrogen attached to an oxygen atom.
  3. Ketones have large dipole moments compared to alcohols or ethers due to the shifting of pi electrons.
  4. Ketones react with hydrogen cyanide to form cyanohydrins. The reaction is normally carried out in the presence of a base, which acts as a catalyst in the absence of a base the reaction proceeds slowly.
  5. Most of the ketones form bisulphite addition products when it is added to sodium bisulphite.

Nomenclature of Ketones

  • Ketones are named after their parent alkanes with the suffix “-anone”. The carbonyl group’s position in the ketone is denoted by a number while naming the ketone. For example, CH3(CO)CHis called 2 propanone. However, this compound is generally referred to as acetone.
  • Commonly, ketones are named by writing the name of each individual alkyl group attached to the carbonyl carbon and then “ketone”as the third word of the name. For example, butanone can be written as methyl ethyl ketone.

Formula

Common name

IUPAC name

CH3-C(O)-CH3

Acetone

Propanone

CH3-C(O)-CH2-CH3

Ethylmethylketone

Butanone

CH3-CH2-C(O)-CH2-CH3

Diethyl ketone

Pentan-3-one

CH3-CH(CH3)-C(O)-CH3

Isopropyl methyl ketone

3-Methylbutan-2-one

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